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Treatment training for advocates

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Index 1.7 CD4: surrogate marker 1.8 CD4: HIV progression 1.9 Interpreting CD4 results

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Glossary Hide

ARV anti-retroviral (drug to treat HIV infection).

CD4 cell white blood cell (lymphocyte) in your immune system that signals to other white blood cells to destroy a virus. CD4 cells are also used by HIV to reproduce.

CD4 count number of CD4 cells in a drop of your blood. CD4 counts are measured in cells/mm3.

HIV human immunodeficiency virus.

seroconversion developing antibodies to the HIV virus. Some people become very ill during seroconversion, others do not.

Resources and downloads Hide

CD4 and viral load PowerPoint 93 Kb

Immune system and CD4 count PDF 225 Kb

1 Immune system and CD4 count

1.8 How quickly does HIV progress in different people?


The time it takes for HIV to affect the immune system varies in different people.

For example, the time it takes for the CD4 count to drop to 200 cells/mm3 can be longer or shorter for different individuals.

Sometimes people who have very serious illness when they are first infected (during seroconversion) will lose CD4 cells more quickly.

There is no way to guess how quickly HIV will progress, other than by monitoring their CD4 count over time.

People who progress more quickly, and who lose CD4 cells more quickly, will still get as good and as strong a response to treatment, as people who progress more slowly.

Approximate time for CD4 count to drop to 200 cells/mm3

Index 1.7 CD4: surrogate marker 1.8 CD4: HIV progression 1.9 Interpreting CD4 results

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Last updated on Monday 26th November 2007.

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